effect of letrozole on endometriosis-related pelvic pain
نویسندگان
چکیده
background : to determine the role of letrozole, an aromatase inhibitor,in the treatment of endometriotic pain. methods: in this prospective, randomized, controlled clinical trial in minimallyinvasive surgery research center,51 women with pelvic endometriosis and endometriotic pain (dyspareunia, dysmenorrhea, pelvic pain) score of 5 or more (for at least one of these endometriotic pain), after laparoscopic diagnosis and conservative laparoscopic surgery were treated with either letrozole plus ocp (n=25) or only ocp (n=26) for 4 months continuously. results: using vas test, the score of dyspareunia, dysmenorrhea and pelvic pain 4 months after the laparoscopic surgery declined significantly in both groups but the difference between results of the two groups was not significant. conclusion: both treatment modalities showed comparable effectiveness in the treatment of pains related to endometriosis and in comparison with ocp, letrozole did not affect the outcome.
منابع مشابه
Effect of Letrozole on endometriosis-related pelvic pain
Background : To determine the role of Letrozole, an aromatase inhibitor,in the treatment of endometriotic pain. Methods: In this prospective, randomized, controlled clinical trial in minimallyinvasive surgery research center,51 women with pelvic endometriosis and endometriotic pain (dyspareunia, dysmenorrhea, pelvic pain) score of 5 or more (for at least one of these endometriotic pain), af...
متن کاملEffect of Letrozole on endometriosis-related pelvic pain
BACKGROUND To determine the role of Letrozole, an aromatase inhibitor, in the treatment of endometriotic pain. METHODS In this prospective, randomized, controlled clinical trial in minimally invasive surgery research center, 51 women with pelvic endometriosis and endometriotic pain (dyspareunia, dysmenorrhea, pelvic pain) score of 5 or more (for at least one of these endometriotic pain), afte...
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BACKGROUND When aromatase inhibitors are used to treat premenopausal women with endometriosis, additional drugs should be used to effectively down-regulate gonadal estrogen biosynthesis. This randomized prospective open-label study compared the efficacy in treating pain symptoms and the tolerability of letrozole combined with either norethisterone acetate or triptorelin. METHODS Women with pa...
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Chronic pelvic pain (CPP) could be considered nowadays a deep health problem that challenges physicians all over the world. This because its aetiology is still unclear, the course of the disease could vary a lot among different patients and through time in the same patient, and the response to treatments is not every time successful. Among women who underwent laparoscopy for CPP, endometriosis ...
متن کاملHormonal treatment for endometriosis associated pelvic pain
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عنوان ژورنال:
medical journal of islamic republic of iranجلد ۲۸، شماره ۱، صفحات ۶۹۵-۷۰۱
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